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Indication


Status


HBN-1 (Intravenous)

Post-Cardiac Resuscitation


Traumatic Brain Injury


Acute Ischemic Stroke


Spinal Cord Injury


Sepsis: severe sepsis and septic shock


Proof-of-Concept Pilot Study Planned


NIH CMC/TOX support to IND for all indications

Existing and new translational models being developed

Spinal injury study collaboration

HBN-2 (Oral)

Mild concussion


Progeria

 


Hot flashes


To be evaluated in NFL concussion model


Progeria mouse model collaboration

Rapid regulatory pathway


Preclinical


HBN-3 and HBN-4 (Intravenous)

Two drugs for severe sepsis & septic shock


Comprehensive preclinical program completed


HBN-Device

Extracorporeal device to eliminate pathogens in severe sepsis & septic shock


Testing collaboration with College of Nanotech Sciences & Engineering at Albany